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1.
Patterns (N Y) ; 1(9): 100173, 2020 Dec 11.
Article in English | MEDLINE | ID: covidwho-1265822

ABSTRACT

[This corrects the article DOI: 10.1016/j.patter.2020.100092.].

2.
Patterns (N Y) ; 1(6): 100092, 2020 Sep 11.
Article in English | MEDLINE | ID: covidwho-692873

ABSTRACT

The emergence of the novel coronavirus disease 2019 (COVID-19) is placing an increasing burden on healthcare systems. Although the majority of infected patients experience non-severe symptoms and can be managed at home, some individuals develop severe symptoms and require hospital admission. Therefore, it is critical to efficiently assess the severity of COVID-19 and identify hospitalization priority with precision. In this respect, a four-variable assessment model, including lymphocyte, lactate dehydrogenase, C-reactive protein, and neutrophil, is established and validated using the XGBoost algorithm. This model is found to be effective in identifying severe COVID-19 cases on admission, with a sensitivity of 84.6%, a specificity of 84.6%, and an accuracy of 100% to predict the disease progression toward rapid deterioration. It also suggests that a computation-derived formula of clinical measures is practically applicable for healthcare administrators to distribute hospitalization resources to the most needed in epidemics and pandemics.

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